COSMOS Symposium on Computational Tools for Safety Assessment Focussing on Cosmetics Ingredients

The Symposium was held on 9 September 2015 at Liverpool John Moores University, UK.

The one day workshop event presented the findings of the EU COSMOS Project, within the context of SEURAT-1.

Specific highlights included:

  • Role of 21st Century Toxicology:
    Development of non-test methods to meet the demands of the Cosmetics legislation
    A database solution to investigate toxicological data to support knowledge discovery and safety evaluation
  • Threshold of Toxicological Concern (TTC):
    The COSMOS TTC dataset enriched in cosmetics-related chemicals, available within COSMOS DB
  • Biokinetics Modelling:
    Freely available PBK models (for oral and dermal exposure), IVIVE, cell-based virtual assays
  • Toxicity Modelling:
    Structural alerts and molecular modelling profilers to support toxicity prediction
  • Computational Workflows:
    Freely available KNIME workflows, KNIME WebPortal, supporting documentation, user guidance and on-line tutorials
  • Read-Across:
    Presentation of a strategy and templates to define uncertainty and assist in data gap filling
  • Hands-On Demonstrations:
    Use the computational tools under expert guidance
  • Interactive feedback opportunities:
    Ask the developers, discuss applications


Time and Date: 9.00am – 5.00pm on Wednesday 9 September 2015

Location: Liverpool John Moores University, Liverpool, England

Cost: Free registration including refreshments and lunch



For downloading the programme click here.

Online Webcast

The Symposium presentations were also broadcasted live online via WebEx.

Recordings of the Presentations

The Symposium has been recorded, the recorded presentations will be made available shortly.

If you are interested in the links to the recordings, let us know at so we can notify you when they become available.


Liverpool John Moores University
James Parsons Building
Byrom Street
Liverpool, L3 3AF



This is European Comission Project. Seventh Framework Programme. Cosmetics Europe, The Personal Care Association. COLIPA, The European trade association for the cosmetic, toiletry and perfumery industry.